| Diagnostic Libi pharm holds IP, manufacturing and distributing medical divice SMARTube ™. The SMARTube ™ is a medical device technology focuses on the preliminary preparation of blood samples for early diagnoses of HIV and hepatitis C (HCV) in order to solve the serological window period problem by reducing the amount of time from infection to detectection. As a blood pretreatment device, SMARTube enhances in vitro antibody production by cells / lymphocytes that have been primed with the virus, with further detection of synthesized antibodies by standard immunological methods (www.smartube.us). SMARTube ™ can also be used in any study aimed at detecting antibodies in human blood, including serological testing simultaneously for IgA, IgM and IgG antibodies related to coronavirus infection COVID-19 (strain SARS-CoV-2). The problem of testing infected SARS-CoV-2 during the infectious process is a relatively long "serological window" from the moment of infection to seroconversion. It was reported by leading scientific journal that in about 50% of the SARS-CoV-2 patients is impossible to detect the virus and any type of related antibodies. It is important to note that the detection of antibodies after pre-treatment in the SMARTube ™ does not depend on the length of the window period. In addition, the SARS-CoV-2 virus is possibly present in other tissues (such as the liver in HCV or the intestinal mucosa and lymph nodes in HIV), not in the blood, and therefore gives false-negative PCR tests. Since the "SMARTube ™" operates on the basis of detecting primed lymphocytes circulating in the blood, which allows you to diagnose an infection, the study using "SMART-tube ™" does not depend on the location of the virus in the body and its degree of latency. Testing with SMARTube for IgM allows you to determine the fact of recent infection with the virus and for IgG, the presence of infection in the later stages of the disease. Using SMARTube ™, it is possible to identify hidden carriers of infection on SARS-Cov-2, people who have had a history of the disease, potential plasma donors with high levels of anti-SARS-Cov-2 antibodies, and exclude patients with suspected infection with SARS-Cov-2. |
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